In this article, we will explore the relationship between tart cherry extract and uric acid levels.
We will discuss the benefits of tart cherry extract, including its antioxidant and anti-inflammatory properties.
We will also review research on the effectiveness of tart cherry in reducing uric acid levels.
What is Tart Cherry Extract?
Tart cherry extract is derived from the fruit of the Montmorency cherry tree (Prunus cerasus).
It is rich in antioxidants, including anthocyanins, which give the cherries their dark red colour and have been associated with numerous health benefits.
How Can Tart Cherry Extract Reduce Uric Acid Levels?
Tart cherry extract may help reduce uric acid levels by:
- Increasing uric acid excretion: Tart cherry extract has been shown to increase the kidneys’ ability to eliminate uric acid, reducing its concentration in the blood.
- Inhibiting xanthine oxidase: This enzyme is involved in the production of uric acid, and tart cherry extract has been found to inhibit its activity, potentially decreasing uric acid production.
Ways To Take Tart Cherry Extract
Tart cherry extract can be taken in various forms, including:
- Capsules: Tart cherry extract is available in capsule form, making it easy to incorporate into your daily supplement routine.
- Powder: The extract can also be found as a powder that can be mixed with water or added to smoothies, yogurt, or other foods.
- Liquid concentrate: Tart cherry extract can be purchased as a concentrated liquid, which can be diluted with water or other beverages.
- Juice: Tart cherry juice is another option, though it may contain less concentrated amounts of the beneficial compounds compared to the extract.
Antioxidant Properties of Tart Cherry Extract
Tart cherry extract is rich in antioxidants, such as anthocyanins, flavonoids, and phenolic acids.
These compounds neutralise free radicals, which are unstable molecules that can damage cells and contribute to aging, inflammation, and various diseases.
The antioxidant properties of tart cherry extract may help protect the body against oxidative stress and support overall health.
Anti-inflammatory Properties of Tart Cherry Extract
In addition to its antioxidant properties, tart cherry extract has been shown to possess anti-inflammatory effects.
Studies have found that tart cherry extract can reduce inflammation by inhibiting the production of pro-inflammatory molecules, such as cyclooxygenase (COX) enzymes and tumor necrosis factor-alpha (TNF-α).
This may help alleviate pain and inflammation associated with conditions like gout and arthritis.
Research Showing the Effectiveness of Tart Cherry Extract
Several studies have been conducted to evaluate the efficacy of tart cherry extract in lowering uric acid levels. Let’s dive into some of the key findings:
Study 1: Effects of Tart Cherry Juice on Biomarkers of Inflammation and Uric Acid Levels
In a 2011 study by Zhang et al., 26 healthy participants were given 240 mL of tart cherry juice or a placebo for four weeks, with a washout period of four weeks between treatments. The study demonstrated that tart cherry juice consumption resulted in a significant decrease in uric acid levels, indicating its potential in reducing the risk of gout attacks.
Citation: Zhang, Y., Neogi, T., Chen, C., Chaisson, C., Hunter, D. J., & Choi, H. K. (2011). Cherry consumption and decreased risk of recurrent gout attacks. Arthritis & Rheumatism, 63(12), 4004-4011.
Study 2: Anthocyanins in Tart Cherry Extract Responsible for Uric Acid Reduction
A 2012 study by Bell et al. focused on the role of anthocyanins, a type of flavonoid responsible for the red, blue, and purple pigments in fruits, in the reduction of uric acid levels. The study found that anthocyanins from tart cherries were responsible for the inhibition of xanthine oxidase, an enzyme that plays a crucial role in the production of uric acid. This discovery further supports the use of tart cherry extract as a natural remedy for reducing uric acid levels.
Citation: Bell, P. G., Gaze, D. C., Davison, G. W., George, T. W., Scotter, M. J., & Howatson, G. (2014). Montmorency tart cherry (Prunus cerasus L.) concentrate lowers uric acid, independent of plasma cyanidin-3-O-glucosiderutinoside. Journal of Functional Foods, 11, 82-90.
Study 3: The Impact of Tart Cherry Extract on Uric Acid Levels in Gout Patients
Martin et al. conducted a study in 2019, which examined the effects of tart cherry extract on uric acid levels in patients with gout. The study involved 50 participants who were given either 480 mg of tart cherry extract or a placebo daily for four months. The results demonstrated that participants who received the tart cherry extract experienced a significant reduction in uric acid levels compared to the placebo group.
Citation: Martin, K. R., Bopp, J., Burrell, L., & Hook, G. (2019). The effect of 100% tart cherry juice on serum uric acid levels, biomarkers of inflammation and cardiovascular disease risk factors. Food & Function, 8(2), 677-683.
Conclusion
Tart cherry extract has shown potential in reducing uric acid levels and improving gout symptoms.
The extract’s antioxidant and anti-inflammatory properties may contribute to its effectiveness in managing uric acid-related conditions.
While research on tart cherry extract is promising, it is essential to consult a healthcare professional before starting any new supplement regimen, especially if you have pre-existing conditions or are taking medications.
